If neurological compromise is noted, urgent treatment is necessary. Monitor patients frequently for signs and symptoms of neurological impairment. Optimal timing between the administration of Enoxaparin Sodium Injection and neuraxial procedures is not known.A history of spinal deformity or spinal surgery.A history of traumatic or repeated epidural or spinal punctures.Concomitant use of other drugs that affect hemostasis, such as non-steroidal anti-inflammatory drugs (NSAIDs), platelet inhibitors, and other anticoagulants.Factors that can increase the risk of developing epidural or spinal hematomas in these patients include: Consider these risks when scheduling patients for spinal procedures. These hematomas may result in longterm or permanent paralysis.
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WARNING: SPINAL/EPIDURAL HEMATOMAS See full prescribing information for complete boxed warning.Įpidural or spinal hematomas may occur in patients who are anticoagulated with low molecular weight heparins (LMWH) or heparinoids and are receiving neuraxial anesthesia or undergoing spinal puncture.
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